The Diagnostic and Treatment Challenges of Concomitant Mantle Cell Lymphoma and IgM Myeloma

It is rare for IgM multiple myeloma Magnet (MM) and mantle cell lymphoma (MCL) to coexist.Furthermore, it is challenging to demonstrate if there are two distinct types of neoplasia or if plasma cell differentiation of MCL is present.We discuss the case of a Cover Ups patient concomitantly diagnosed with MCL and IgM MM, and the subsequent diagnostic and management difficulties, and the positive treatment outcome.